STING-dependent cytosolic DNA sensor pathways regulate NKG2D ligand expression
نویسندگان
چکیده
The DNA damage response (DDR) upregulates the expression of NKG2D ligands (NKG2DLs).1,2 We have recently reported that the DDR also induces the presence of cytosolic DNA in B-cell lymphoma cells, which leads to the activation of STING-dependent cytosolic DNA sensor pathways and the expression of RAE-1 ligands for NKG2D.3.
منابع مشابه
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عنوان ژورنال:
دوره 3 شماره
صفحات -
تاریخ انتشار 2014